8 Hughes is a distinctive office destination in the heart of Irvine — proudly home to HealthQuest Esoterics, a state-of-the-art clinical laboratory, and HealthQuest Wellness, an integrative and regenerative medicine center.
8 Hughes is a two-story office and medical building located at 8 Hughes, Irvine, CA 92618, in the Irvine Spectrum business area of Orange County, California. The building offers office, medical, and laboratory space for lease, with rental rates quoted per square foot per year.
The building is home to HealthQuest Esoterics, a clinical laboratory, and HealthQuest Wellness, an integrative medicine practice in Suite 125. Two additional office suites — 6,980 SF and 9,790 SF — are currently available for lease.
8 Hughes is in Irvine, CA 92618, near Irvine Spectrum, with immediate access to the I-405 and I-5 freeways and minutes from John Wayne Airport. It serves businesses across Orange County, including Lake Forest, Laguna Hills, Tustin, and Costa Mesa.
Available suites are listed at $21.00 per square foot per year with negotiable lease terms. Both suites are full build-out office space and are available now. Contact admin@8hughes.com for current terms.
8 Hughes is more than an office building — it's a center of care and diagnostics. Our anchor tenants bring world-class laboratory science and personalized wellness medicine to Irvine.
A full-service clinical laboratory specializing in toxicology and molecular diagnostics, serving physicians and patients from its facility at 8 Hughes.
An integrative, regenerative, and functional medicine practice helping patients achieve optimal well-being. HealthQuest Wellness combines holistic and evidence-based approaches to treat chronic pain, anxiety, depression, and more.
Rental rates displayed as $/SF/YR. Two full build-out office suites are available now — one on each floor.
| Space | Size | Term | Rental Rate | Space Use | Build-Out | Available |
|---|---|---|---|---|---|---|
| 1st Floor, Ste 150 | 6,980 SF | Negotiable | $21.00 /SF/YR | Office | Full Build-Out | Now |
| 2nd Floor, Ste 210 | 9,790 SF | Negotiable | $21.00 /SF/YR | Office | Full Build-Out | Now |
Rates and availability are subject to change. Contact us at admin@8hughes.com for current terms and to schedule a tour. Current tenant? Submit a maintenance request.
A professionally maintained two-story property with the infrastructure modern medical and office users demand.
Centrally located in Irvine's business district with convenient access to the I-405 and I-5 freeways, John Wayne Airport, and surrounding amenities.
Home to a full clinical laboratory and a wellness practice, the building supports specialized medical, laboratory, and professional office uses.
Mature trees and manicured landscaping create a calm, professional environment for employees, patients, and visitors alike.
Ample surface parking directly adjacent to the building for staff and patient convenience.
Suite configurations suited to professional offices, medical practices, and laboratory operations — ask us about current availability.
A dedicated on-site ownership team ready to assist with leasing questions, layout options, and rental terms.
8 Hughes sits in Irvine's thriving business district in the 92618 zip code — one of Southern California's most sought-after addresses for office, medical, and laboratory space. The building offers immediate access to the I-405 and I-5 freeways, is minutes from John Wayne Airport (SNA), and is a short drive from the Irvine Spectrum Center's dining, retail, and entertainment. Neighboring business communities in Lake Forest, Laguna Hills, Tustin, and Costa Mesa are all within easy reach, making 8 Hughes an ideal home base for companies serving clients across Orange County.
Join a thriving professional community in a prime Irvine location. Our team will gladly provide layout options, rental terms, and amenity details.