Irvine, California

A Premier Address for Health & Science

8 Hughes is a distinctive office destination in the heart of Irvine — proudly home to HealthQuest Esoterics, a state-of-the-art clinical laboratory, and HealthQuest Wellness, an integrative and regenerative medicine center.

Meet Our Tenants Leasing Opportunities

Stories of Office Space

92618

Prime Irvine Zip Code

HealthQuest Anchor Tenants

Suites Available Now

Our Tenants

Two HealthQuest leaders, one address

8 Hughes is more than an office building — it's a center of care and diagnostics. Our anchor tenants bring world-class laboratory science and personalized wellness medicine to Irvine.

Clinical Laboratory

HealthQuest Esoterics

A full-service clinical laboratory specializing in toxicology and molecular diagnostics, serving physicians and patients from its facility at 8 Hughes.

Advanced toxicology & molecular diagnostics testing
PhD-level scientists and custom test development
Mobile phlebotomy and dedicated courier network

949-242-2260 · hqesoterics.com

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Integrative Medicine — Suite 125

HealthQuest Wellness

An integrative, regenerative, and functional medicine practice helping patients achieve optimal well-being. HealthQuest Wellness combines holistic and evidence-based approaches to treat chronic pain, anxiety, depression, and more.

Ozone therapy, ketamine therapy & stellate ganglion blocks
Acupuncture and functional health coaching
Personalized, science-backed treatment plans
Telehealth consultations available

949-420-9010 · hqwellness.org

Learn More

Leasing

All Available Spaces (2)

Rental rates displayed as $/SF/YR. Two full build-out office suites are available now — one on each floor.

Space	Size	Term	Rental Rate	Space Use	Build-Out	Available
1st Floor, Ste 150	6,980 SF	Negotiable	$21.00 /SF/YR	Office	Full Build-Out	Now
2nd Floor, Ste 210	9,790 SF	Negotiable	$21.00 /SF/YR	Office	Full Build-Out	Now

Rates and availability are subject to change. Contact us at admin@8hughes.com for current terms and to schedule a tour. Current tenant? Submit a maintenance request.

The Building

Designed for business to thrive

A professionally maintained two-story property with the infrastructure modern medical and office users demand.

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Prime Irvine Location

Centrally located in Irvine's business district with convenient access to the I-405 and I-5 freeways, John Wayne Airport, and surrounding amenities.

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Medical-Ready Suites

Home to a full clinical laboratory and a wellness practice, the building supports specialized medical, laboratory, and professional office uses.

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Landscaped Grounds

Mature trees and manicured landscaping create a calm, professional environment for employees, patients, and visitors alike.

On-Site Parking

Ample surface parking directly adjacent to the building for staff and patient convenience.

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Flexible Layouts

Suite configurations suited to professional offices, medical practices, and laboratory operations — ask us about current availability.

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Responsive Management

A dedicated on-site ownership team ready to assist with leasing questions, layout options, and rental terms.

Location

Office space near Irvine Spectrum, in the heart of Orange County

8 Hughes sits in Irvine's thriving business district in the 92618 zip code — one of Southern California's most sought-after addresses for office, medical, and laboratory space. The building offers immediate access to the I-405 and I-5 freeways, is minutes from John Wayne Airport (SNA), and is a short drive from the Irvine Spectrum Center's dining, retail, and entertainment. Neighboring business communities in Lake Forest, Laguna Hills, Tustin, and Costa Mesa are all within easy reach, making 8 Hughes an ideal home base for companies serving clients across Orange County.

Interested in leasing at 8 Hughes?

Join a thriving professional community in a prime Irvine location. Our team will gladly provide layout options, rental terms, and amenity details.

Get in Touch